CD86 Polyclonal Antibody, Unconjugated, Rabbit
Catalog Number:
BWT-BS65646
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| Article Name: | CD86 Polyclonal Antibody, Unconjugated, Rabbit |
| Biozol Catalog Number: | BWT-BS65646 |
| Supplier Catalog Number: | BS65646 |
| Alternative Catalog Number: | BWT-BS65646-50UL,BWT-BS65646-100UL |
| Manufacturer: | Bioworld Technology |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | IF, IP, WB |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-247 of human CD86 (NP_787058.4). |
| Conjugation: | Unconjugated |
| Alternative Names: | CD28LG2, FUN1, LAB72, Activation B7 2 antigen, Activation B7-2 antigen 3, CD86_HUMAN, Activation B7-2 antigen, Activation B72 antigen, B lymphocyte activation antigen B7 2, B lymphocyte activation antigen B72, B-lymphocyte activation antigen B7-2 2, B-lymphocyte activation antigen B7-2, B7 2, B7 2 antigen, B7, B7-2, B7.2, B70, B72 antigen, BU63, CD 86, CD28 antigen ligand 2 2, CD28 antigen ligand 2, Cd28l2, CD28LG2, CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) 1, 2, CD86 antigen, CD86 molecule, CLS1, CTLA 4 counter receptor B7 2, CTLA 4 counter receptor B7.2, CTLA-4 counter-receptor B7.2 2, 3, CTLA4 counter receptor B72, Early T-cell costimulatory molecule 1, ETC-1, FUN 1, LAB72, Ly-58, Ly58, MB7, MB7-2, Membrane glycoprotein, MGC34413, T lymphocyte activation antigen CD86, T-lymphocyte activation antigen CD86, TS/A-2 |
| This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]. |
| Molecular Weight: | ~ 65-70 kDa |
| UniProt: | P42081 |
| Purity: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
| Form: | Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
| Application Dilute: | WB: 1:100-1:500 IF/ICC: 1:50-1:200 IP: 1:50-1:200 |
| Application Notes: | CD86 Polyclonal Antibody detects endogenous levels of CD86 protein. |
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