Pan Lactic acid-Lysine polyclonal antibody, Unconjugated, Rabbit
Artikelnummer:
BWT-BS66163
Hersteller Artikelnummer:
BS66163
Alternativnummer:
BWT-BS66163-50UL,BWT-BS66163-100UL
Hersteller:
Bioworld Technology
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
WB
Spezies Reaktivität:
Human, Mouse, Rat
Immunogen:
A synthetic peptide corresponding to a sequence containing crotonylated K.
Konjugation:
Unconjugated
Histone lysine lactation (Kla) is a newly discovered histone modification that regulates gene expression in macrophages. In M1 macrophages, lactic acid is derived from incompletely oxidized glucose and then produces lactyl-CoA, which is transferred via acetyltransferase p300 to the lysine tail of the histone. This modification is abundant in gene promoter regions that lack acetylation and are associated with gene expression activation.
Molekulargewicht:
~ 35-130 kDa
Reinheit:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Formulierung:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Verdünnung:
WB 1:500 - 1:2000
Anwendungsbeschreibung:
Pan Lactic acid-Lysine polyclonal antibody detects endogenous levels of Pan Lactic acid-Lysine protein.
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