Pan Lactic acid-Lysine polyclonal antibody, Unconjugated, Rabbit
Biozol Catalog Number:
BWT-BS66163
Supplier Catalog Number:
BS66163
Alternative Catalog Number:
BWT-BS66163-50UL,BWT-BS66163-100UL
Manufacturer:
Bioworld Technology
Host:
Rabbit
Category:
Antikörper
Application:
WB
Species Reactivity:
Human, Mouse, Rat
Immunogen:
A synthetic peptide corresponding to a sequence containing crotonylated K.
Conjugation:
Unconjugated
Histone lysine lactation (Kla) is a newly discovered histone modification that regulates gene expression in macrophages. In M1 macrophages, lactic acid is derived from incompletely oxidized glucose and then produces lactyl-CoA, which is transferred via acetyltransferase p300 to the lysine tail of the histone. This modification is abundant in gene promoter regions that lack acetylation and are associated with gene expression activation.
Molecular Weight:
~ 35-130 kDa
Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Form:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Dilute:
WB 1:500 - 1:2000
Application Notes:
Pan Lactic acid-Lysine polyclonal antibody detects endogenous levels of Pan Lactic acid-Lysine protein.
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