[KO Validated] MYOF polyclonal antibody, Unconjugated, Rabbit

Artikelnummer: BWT-BS72594
Artikelname: [KO Validated] MYOF polyclonal antibody, Unconjugated, Rabbit
Artikelnummer: BWT-BS72594
Hersteller Artikelnummer: BS72594
Alternativnummer: BWT-BS72594-50UL,BWT-BS72594-100UL
Hersteller: Bioworld Technology
Wirt: Rabbit
Kategorie: Antikörper
Applikation: WB
Spezies Reaktivität: Human, Mouse
Immunogen: Recombinant fusion protein of human MYOF(NP_038479.1).
Konjugation: Unconjugated
Alternative Synonym: MYOF,FER1L3,myoferlin
Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined.
Molekulargewicht: 250KDa
UniProt: Q9NZM1
Reinheit: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Formulierung: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Verdünnung: WB,1:200 - 1:2000
Anwendungsbeschreibung: Polyclonal Antibodies