[KO Validated] MYOF polyclonal antibody, Unconjugated, Rabbit

Catalog Number: BWT-BS72594
Article Name: [KO Validated] MYOF polyclonal antibody, Unconjugated, Rabbit
Biozol Catalog Number: BWT-BS72594
Supplier Catalog Number: BS72594
Alternative Catalog Number: BWT-BS72594-50UL,BWT-BS72594-100UL
Manufacturer: Bioworld Technology
Host: Rabbit
Category: Antikörper
Application: WB
Species Reactivity: Human, Mouse
Immunogen: Recombinant fusion protein of human MYOF(NP_038479.1).
Conjugation: Unconjugated
Alternative Names: MYOF,FER1L3,myoferlin
Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined.
Molecular Weight: 250KDa
UniProt: Q9NZM1
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Form: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Dilute: WB,1:200 - 1:2000
Application Notes: Polyclonal Antibodies