FCN1 polyclonal antibody, Unconjugated, Rabbit

Produktübersicht

• Artikelname: FCN1 polyclonal antibody, Unconjugated, Rabbit
• Artikelnummer: BWT-BS8271
• Hersteller Artikelnummer: BS8271
• Alternativnummer: BWT-BS8271-50UL,BWT-BS8271-100UL
• Hersteller: Bioworld Technology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: Recombinant full length Human FCN1.
• Konjugation: Unconjugated
• Alternative Synonym: Ficolin-1, Collagen/fibrinogen domain-containing protein 1, Ficolin-A, Ficolin-alpha, M-ficolin, FCN1, FCNM

Produktbeschreibung

M-ficolin, also known as ficolin-A, ficolin-1, ficolin-alpha, FCN1, FCNM or collagen/fibrinogen domain containing protein 1, is a 326 amino acid member of the ficolin lectin family. Characteristic of ficolin family proteins, M-ficolin contains a short N-terminus, one collagen-like domain and one fibrinogen-like domain at its C-terminus. M-ficolin is a secreted innate immunity pattern recognition molecule predominantly expressed in peripheral blood leukocytes. It is believed to function as a plasma protein and is known to interact with elastin, carbohydrates and corticosteroids. M-ficolin exists as a homopolymer through intermolecular disulfide bonding and is involved in activating lectin activity via association with MASPs and specific carbohydrate ligands.

Produkteigenschaften

• Molekulargewicht: ~ 35 kDa
• UniProt: O00602
• Reinheit: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
• Formulierung: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Anwendungsbeschreibung

• Application Verdünnung: WB: 1:500~1:2000 IHC: 1:50~1:200
• Anwendungsbeschreibung: FCN1 polyclonal antibody detects endogenous levels of FCN1 protein.