Ficolin-1, Collagen/fibrinogen domain-containing protein 1, Ficolin-A, Ficolin-alpha, M-ficolin, FCN1, FCNM
M-ficolin, also known as ficolin-A, ficolin-1, ficolin-alpha, FCN1, FCNM or collagen/fibrinogen domain containing protein 1, is a 326 amino acid member of the ficolin lectin family. Characteristic of ficolin family proteins, M-ficolin contains a short N-terminus, one collagen-like domain and one fibrinogen-like domain at its C-terminus. M-ficolin is a secreted innate immunity pattern recognition molecule predominantly expressed in peripheral blood leukocytes. It is believed to function as a plasma protein and is known to interact with elastin, carbohydrates and corticosteroids. M-ficolin exists as a homopolymer through intermolecular disulfide bonding and is involved in activating lectin activity via association with MASPs and specific carbohydrate ligands.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Form:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Dilute:
WB: 1:500~1:2000 IHC: 1:50~1:200
Application Notes:
FCN1 polyclonal antibody detects endogenous levels of FCN1 protein.
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