DGCR8 polyclonal antibody, Unconjugated, Rabbit

Produktübersicht

• Artikelname: DGCR8 polyclonal antibody, Unconjugated, Rabbit
• Artikelnummer: BWT-BZ16637
• Hersteller Artikelnummer: BZ16637
• Alternativnummer: BWT-BZ16637-50UL,BWT-BZ16637-100UL
• Hersteller: Bioworld Technology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ICC, IP, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: A synthesized peptide derived from human DGCR8
• Konjugation: Unconjugated
• Alternative Synonym: DGCR8, DGCRK6, Gy1, C22orf12, D16Wis2, pasha

Produktbeschreibung

Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DGCR8 function as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junction and directs DROSHA to cleave 11 bp away form the junction to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs.

Produkteigenschaften

• Molekulargewicht: Calculated MW: 86 kDa, Observed MW: 100 kDa
• UniProt: Q8WYQ5
• Reinheit: Affinity Purified
• Formulierung: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Anwendungsbeschreibung

• Application Verdünnung: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
• Anwendungsbeschreibung: IgG