DGCR8 polyclonal antibody, Unconjugated, Rabbit

Product Overview

• Article Name: DGCR8 polyclonal antibody, Unconjugated, Rabbit
• Biozol Catalog Number: BWT-BZ16637
• Supplier Catalog Number: BZ16637
• Alternative Catalog Number: BWT-BZ16637-50UL,BWT-BZ16637-100UL
• Manufacturer: Bioworld Technology
• Host: Rabbit
• Category: Antikörper
• Application: ICC, IP, WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: A synthesized peptide derived from human DGCR8
• Conjugation: Unconjugated
• Alternative Names: DGCR8, DGCRK6, Gy1, C22orf12, D16Wis2, pasha

Product Description

Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DGCR8 function as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junction and directs DROSHA to cleave 11 bp away form the junction to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs.

Product Properties

• Molecular Weight: Calculated MW: 86 kDa, Observed MW: 100 kDa
• UniProt: Q8WYQ5
• Purity: Affinity Purified
• Form: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application Notes

• Application Dilute: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
• Application Notes: IgG