Phospho-IRE1 (Ser724) polyclonal antibody, Unconjugated, Rabbit
Artikelnummer:
BWT-BZ16653
Produktübersicht
Artikelname:
Phospho-IRE1 (Ser724) polyclonal antibody, Unconjugated, Rabbit
Artikelnummer:
BWT-BZ16653
Hersteller Artikelnummer:
BZ16653
Alternativnummer:
BWT-BZ16653-50UL,BWT-BZ16653-100UL
Hersteller:
Bioworld Technology
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
WB
Spezies Reaktivität:
Human
Immunogen:
A synthesized peptide derived from human Phospho-IRE1 (S724)
Konjugation:
Unconjugated
Alternative Synonym:
ERN1, IRE1, Serine/threonine-protein kinase/endoribonuclease IRE1, Endoplasmic reticulum-to-nucleus signaling 1, Inositol-requiring protein 1, hIRE1p, Ire1-alpha, IRE1a
Produktbeschreibung
Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
Produkteigenschaften
Molekulargewicht:
Calculated MW: 110 kDa, Observed MW: 110 kDa
UniProt:
O75460
Reinheit:
Affinity Purified
Formulierung:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Anwendungsbeschreibung
Application Verdünnung:
WB: 1/500-1/1000
Anwendungsbeschreibung:
IgG
