Phospho-IRE1 (Ser724) polyclonal antibody, Unconjugated, Rabbit

Product Overview

• Article Name: Phospho-IRE1 (Ser724) polyclonal antibody, Unconjugated, Rabbit
• Biozol Catalog Number: BWT-BZ16653
• Supplier Catalog Number: BZ16653
• Alternative Catalog Number: BWT-BZ16653-50UL,BWT-BZ16653-100UL
• Manufacturer: Bioworld Technology
• Host: Rabbit
• Category: Antikörper
• Application: WB
• Species Reactivity: Human
• Immunogen: A synthesized peptide derived from human Phospho-IRE1 (S724)
• Conjugation: Unconjugated
• Alternative Names: ERN1, IRE1, Serine/threonine-protein kinase/endoribonuclease IRE1, Endoplasmic reticulum-to-nucleus signaling 1, Inositol-requiring protein 1, hIRE1p, Ire1-alpha, IRE1a

Product Description

Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.

Product Properties

• Molecular Weight: Calculated MW: 110 kDa, Observed MW: 110 kDa
• UniProt: O75460
• Purity: Affinity Purified
• Form: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application Notes

• Application Dilute: WB: 1/500-1/1000
• Application Notes: IgG