SMAC polyclonal antibody, Unconjugated, Rabbit

Produktübersicht

• Artikelname: SMAC polyclonal antibody, Unconjugated, Rabbit
• Artikelnummer: BWT-BZ16678
• Hersteller Artikelnummer: BZ16678
• Alternativnummer: BWT-BZ16678-50UL,BWT-BZ16678-100UL
• Hersteller: Bioworld Technology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: FC, ICC, IHC-P, IP, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: A synthesized peptide derived from human Smac/Diablo
• Konjugation: Unconjugated
• Alternative Synonym: SMAC, DFNA64, DIABLO, SMAC3

Produktbeschreibung

Smac/Diablo is a 21 kDa mammalian mitochondrial protein that functions as a regulatory component during apoptosis. Upon mitochondrial stress, Smac/Diablo is released from mitochondria and competes with caspases for binding of IAPs (inhibitor of apoptosis proteins). The interaction of Smac/Diablo with IAPs relieves the inhibitory effect of the IAPs on caspases.

Produkteigenschaften

• Molekulargewicht: Calculated MW: 27 kDa, Observed MW: 21 kDa
• UniProt: Q9NR28
• Reinheit: Affinity Purified
• Formulierung: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Anwendungsbeschreibung

• Application Verdünnung: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100
• Anwendungsbeschreibung: IgG