SMAC polyclonal antibody, Unconjugated, Rabbit

Product Overview

• Article Name: SMAC polyclonal antibody, Unconjugated, Rabbit
• Biozol Catalog Number: BWT-BZ16678
• Supplier Catalog Number: BZ16678
• Alternative Catalog Number: BWT-BZ16678-50UL,BWT-BZ16678-100UL
• Manufacturer: Bioworld Technology
• Host: Rabbit
• Category: Antikörper
• Application: FC, ICC, IHC-P, IP, WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: A synthesized peptide derived from human Smac/Diablo
• Conjugation: Unconjugated
• Alternative Names: SMAC, DFNA64, DIABLO, SMAC3

Product Description

Smac/Diablo is a 21 kDa mammalian mitochondrial protein that functions as a regulatory component during apoptosis. Upon mitochondrial stress, Smac/Diablo is released from mitochondria and competes with caspases for binding of IAPs (inhibitor of apoptosis proteins). The interaction of Smac/Diablo with IAPs relieves the inhibitory effect of the IAPs on caspases.

Product Properties

• Molecular Weight: Calculated MW: 27 kDa, Observed MW: 21 kDa
• UniProt: Q9NR28
• Purity: Affinity Purified
• Form: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application Notes

• Application Dilute: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100
• Application Notes: IgG