Transcription Factor 7 Like 2 polyclonal antibody, Unconjugated, Rabbit

Produktübersicht

• Artikelname: Transcription Factor 7 Like 2 polyclonal antibody, Unconjugated, Rabbit
• Artikelnummer: BWT-BZ16685
• Hersteller Artikelnummer: BZ16685
• Alternativnummer: BWT-BZ16685-50UL,BWT-BZ16685-100UL
• Hersteller: Bioworld Technology
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: FC, ICC, IHC-P, IP, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: A synthesized peptide derived from human TCF7L2
• Konjugation: Unconjugated
• Alternative Synonym: TCF7L2, HMG box transcription factor 4, HTCF-4, T-cell factor-4 variant X2, T-cell factor 4, Transcription factor 7-like 2, TCF-4

Produktbeschreibung

Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner. Acts as repressor in the absence of CTNNB1, and as activator in its presence. Activates transcription from promoters with several copies of the Tcf motif 5-CCTTTGATC-3 in the presence of CTNNB1. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7L2/TCF4 and CTNNB1.

Produkteigenschaften

• Molekulargewicht: Calculated MW: 68 kDa, Observed MW: 68 kDa
• UniProt: Q9NQB0
• Reinheit: Affinity Purified
• Formulierung: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Anwendungsbeschreibung

• Application Verdünnung: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100
• Anwendungsbeschreibung: IgG