Transcription Factor 7 Like 2 polyclonal antibody, Unconjugated, Rabbit

Product Overview

• Article Name: Transcription Factor 7 Like 2 polyclonal antibody, Unconjugated, Rabbit
• Biozol Catalog Number: BWT-BZ16685
• Supplier Catalog Number: BZ16685
• Alternative Catalog Number: BWT-BZ16685-50UL,BWT-BZ16685-100UL
• Manufacturer: Bioworld Technology
• Host: Rabbit
• Category: Antikörper
• Application: FC, ICC, IHC-P, IP, WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: A synthesized peptide derived from human TCF7L2
• Conjugation: Unconjugated
• Alternative Names: TCF7L2, HMG box transcription factor 4, HTCF-4, T-cell factor-4 variant X2, T-cell factor 4, Transcription factor 7-like 2, TCF-4

Product Description

Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner. Acts as repressor in the absence of CTNNB1, and as activator in its presence. Activates transcription from promoters with several copies of the Tcf motif 5-CCTTTGATC-3 in the presence of CTNNB1. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7L2/TCF4 and CTNNB1.

Product Properties

• Molecular Weight: Calculated MW: 68 kDa, Observed MW: 68 kDa
• UniProt: Q9NQB0
• Purity: Affinity Purified
• Form: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application Notes

• Application Dilute: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100
• Application Notes: IgG