Ki67 monoclonal antibody, Unconjugated, Mouse

Artikelnummer: BWT-MB66076
Artikelname: Ki67 monoclonal antibody, Unconjugated, Mouse
Artikelnummer: BWT-MB66076
Hersteller Artikelnummer: MB66076
Alternativnummer: BWT-MB66076-50UL,BWT-MB66076-100UL
Hersteller: Bioworld Technology
Wirt: Mouse
Kategorie: Antikörper
Applikation: IF, IHC
Spezies Reaktivität: Human
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within human Ki67. The exact sequence is proprietary.
Konjugation: Unconjugated
Alternative Synonym: Antigen KI-67
Ki-67, named after the location where it was discovered (Kiel University, Germany), is a nuclear nonhistone protein that is universally expressed among proliferating cells and absent in quiescent cells. Ki-67 detects proliferating cells in G1, S, G2, and mitosis, but not in the G0 resting phase. Research studies have shown that high levels of Ki-67 are associated with poorer breast cancer survival. Research studies have explored the use of Ki-67, along with other markers, as potential prognostic or predictive markers in breast cancer and other malignant diseases.
Molekulargewicht: ~ 358 kDa
UniProt: P46013
Reinheit: The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Formulierung: Mouse IgG1. Liquid in PBS containing 50% glycerol, 0.2% BSA and 0.01% sodium azide.
Application Verdünnung: IHC (1/100 - 1/300), IF (1/100 - 1/500)
Anwendungsbeschreibung: Recognizes endogenous levels of Ki67 protein.