KLH-conjugated synthetic peptide encompassing a sequence within human Ki67. The exact sequence is proprietary.
Conjugation:
Unconjugated
Alternative Names:
Antigen KI-67
Ki-67, named after the location where it was discovered (Kiel University, Germany), is a nuclear nonhistone protein that is universally expressed among proliferating cells and absent in quiescent cells. Ki-67 detects proliferating cells in G1, S, G2, and mitosis, but not in the G0 resting phase. Research studies have shown that high levels of Ki-67 are associated with poorer breast cancer survival. Research studies have explored the use of Ki-67, along with other markers, as potential prognostic or predictive markers in breast cancer and other malignant diseases.
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Form:
Mouse IgG1. Liquid in PBS containing 50% glycerol, 0.2% BSA and 0.01% sodium azide.
Application Dilute:
IHC (1/100 - 1/300), IF (1/100 - 1/500)
Application Notes:
Recognizes endogenous levels of Ki67 protein.
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