PE mouse anti-human CD19 monoclonal antibody, Unconjugated, Mouse
Artikelnummer:
BWT-MB8613P
Hersteller Artikelnummer:
MB8613P
Alternativnummer:
BWT-MB8613P-25TESTS,BWT-MB8613P-100UL
Hersteller:
Bioworld Technology
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
FC
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
CD19 is expressed on follicular dendritic cells and B cells. In fact, it is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells. It primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Src-family kinases and recruitment of PI-3 kinase.
