PE mouse anti-human CD19 monoclonal antibody, Unconjugated, Mouse
Biozol Catalog Number:
BWT-MB8613P
Supplier Catalog Number:
MB8613P
Alternative Catalog Number:
BWT-MB8613P-25TESTS,BWT-MB8613P-100UL
Manufacturer:
Bioworld Technology
Host:
Mouse
Category:
Antikörper
Application:
FC
Species Reactivity:
Human
Conjugation:
Unconjugated
CD19 is expressed on follicular dendritic cells and B cells. In fact, it is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells. It primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Src-family kinases and recruitment of PI-3 kinase.
