VU 0240551, CAS [[893990-34-6]]

Artikelnummer: BYT-ORB1296176
Artikelname: VU 0240551, CAS [[893990-34-6]]
Artikelnummer: BYT-ORB1296176
Hersteller Artikelnummer: orb1296176
Alternativnummer: BYT-ORB1296176-1, BYT-ORB1296176-1, BYT-ORB1296176-10, BYT-ORB1296176-100, BYT-ORB1296176-200, BYT-ORB1296176-25, BYT-ORB1296176-5, BYT-ORB1296176-50, BYT-ORB1296176-500
Hersteller: Biorbyt
Kategorie: Biochemikalien
Alternative Synonym: hERG, L-type calcium channel, KCC2, Calcium Channel, CalciumChannel, PotassiumChannel, Potassium Channel, VU0240551, VU-0240551, VU 0240551
VU 0240551 is a selective, small-molecule antagonist of the neuronal K-Cl cotransporter KCC2, exhibiting an IC50 of 560 nM. It also demonstrates off-target activity by inhibiting L-type calcium channels and the hERG potassium channel. This compound is utilized in neuroscience research to investigate GABAergic signaling, neuronal excitability, and related pathophysiology in both cellular and animal models.
Molekulargewicht: 342.44
Reinheit: 99.90% (May vary between batches)
CAS Nummer: [893990-34-6]
Formel: C16H14N4OS2
Target-Kategorie: Calcium Channel,Potassium Channel
Anwendungsbeschreibung: Solubility: H2O:Insoluble,DMSO:45 mg/mL (131.41 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.84 mM)