VU 0240551, CAS [[893990-34-6]]

Product Overview

• Article Name: VU 0240551, CAS [[893990-34-6]]
• Biozol Catalog Number: BYT-ORB1296176
• Supplier Catalog Number: orb1296176
• Alternative Catalog Number: BYT-ORB1296176-1, BYT-ORB1296176-1, BYT-ORB1296176-10, BYT-ORB1296176-100, BYT-ORB1296176-200, BYT-ORB1296176-25, BYT-ORB1296176-5, BYT-ORB1296176-50, BYT-ORB1296176-500
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: hERG, L-type calcium channel, KCC2, Calcium Channel, CalciumChannel, PotassiumChannel, Potassium Channel, VU0240551, VU-0240551, VU 0240551

Product Description

VU 0240551 is a selective, small-molecule antagonist of the neuronal K-Cl cotransporter KCC2, exhibiting an IC50 of 560 nM. It also demonstrates off-target activity by inhibiting L-type calcium channels and the hERG potassium channel. This compound is utilized in neuroscience research to investigate GABAergic signaling, neuronal excitability, and related pathophysiology in both cellular and animal models.

Product Properties

• Molecular Weight: 342.44
• Purity: 99.90% (May vary between batches)
• CAS Number: [893990-34-6]
• Formula: C16H14N4OS2
• Target: Calcium Channel,Potassium Channel

Application Notes

• Application Notes: Solubility: H2O:Insoluble,DMSO:45 mg/mL (131.41 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.84 mM)