K145 hydrochloride, CAS [[1449240-68-9]]

Artikelnummer: BYT-ORB1296177
Artikelname: K145 hydrochloride, CAS [[1449240-68-9]]
Artikelnummer: BYT-ORB1296177
Hersteller Artikelnummer: orb1296177
Alternativnummer: BYT-ORB1296177-10, BYT-ORB1296177-25, BYT-ORB1296177-5, BYT-ORB1296177-50
Hersteller: Biorbyt
Kategorie: Biochemikalien
Alternative Synonym: antitumor, anti-proliferative, Apoptosis, apoptotic, Akt, ERK, Inhibitor, oral, K 145, K 145 Hydrochloride, K145, K-145, K145 hydrochloride, K145 Hydrochloride, K-145 Hydrochloride, K-145 hydrochloride, inhibit, SphK2, SphK, sphingosine, Sphingosine kinase, S1PReceptor, substrate-competitive, S1P Receptor, S1P
K145 hydrochloride is an orally active, substrate-competitive, and selective SphK2 inhibitor (IC50 = 4.3 µM, K = 6.4 µM). It exhibits potent antitumor activity by inducing apoptosis, making it a valuable tool for oncology research in both cellular and animal models of cancer.
Molekulargewicht: 384.92
Reinheit: 99.80% (May vary between batches)
CAS Nummer: [1449240-68-9]
Formel: C18H25ClN2O3S
Target-Kategorie: S1P Receptor,Apoptosis
Anwendungsbeschreibung: Solubility: 10% DMSO+40% PEG300+5% Tween-80+45% Saline:1 mg/mL (2.6 mM),H2O:125 mg/mL (324.74 mM),DMSO:45 mg/mL (116.91 mM)