K145 hydrochloride, CAS [[1449240-68-9]]

Product Overview

• Article Name: K145 hydrochloride, CAS [[1449240-68-9]]
• Biozol Catalog Number: BYT-ORB1296177
• Supplier Catalog Number: orb1296177
• Alternative Catalog Number: BYT-ORB1296177-10, BYT-ORB1296177-25, BYT-ORB1296177-5, BYT-ORB1296177-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: antitumor, anti-proliferative, Apoptosis, apoptotic, Akt, ERK, Inhibitor, oral, K 145, K 145 Hydrochloride, K145, K-145, K145 hydrochloride, K145 Hydrochloride, K-145 Hydrochloride, K-145 hydrochloride, inhibit, SphK2, SphK, sphingosine, Sphingosine kinase, S1PReceptor, substrate-competitive, S1P Receptor, S1P

Product Description

K145 hydrochloride is an orally active, substrate-competitive, and selective SphK2 inhibitor (IC50 = 4.3 µM, K = 6.4 µM). It exhibits potent antitumor activity by inducing apoptosis, making it a valuable tool for oncology research in both cellular and animal models of cancer.

Product Properties

• Molecular Weight: 384.92
• Purity: 99.80% (May vary between batches)
• CAS Number: [1449240-68-9]
• Formula: C18H25ClN2O3S
• Target: S1P Receptor,Apoptosis

Application Notes

• Application Notes: Solubility: 10% DMSO+40% PEG300+5% Tween-80+45% Saline:1 mg/mL (2.6 mM),H2O:125 mg/mL (324.74 mM),DMSO:45 mg/mL (116.91 mM)