VH-298, CAS [[2097381-85-4]]

Artikelnummer: BYT-ORB1296188
Artikelname: VH-298, CAS [[2097381-85-4]]
Artikelnummer: BYT-ORB1296188
Hersteller Artikelnummer: orb1296188
Alternativnummer: BYT-ORB1296188-1, BYT-ORB1296188-10, BYT-ORB1296188-100, BYT-ORB1296188-2, BYT-ORB1296188-25, BYT-ORB1296188-5, BYT-ORB1296188-50
Hersteller: Biorbyt
Kategorie: Biochemikalien
Alternative Synonym: VH298, VH-298, VH 298, VHL, E3 ligase-recruiting Moiety, HIF-1alpha, Inhibitor, inhibit, Ligands for E3 Ligase, LigandforE3Ligase, Ligand for E3 Ligase
VH-298 is a cell-permeable small molecule that potently inhibits the VHL-HIF-alpha interaction, stabilizing HIF-alpha and inducing a hypoxic response independent of PHD enzyme inhibition. It is a valuable chemical probe for studying hypoxia signaling pathways and has demonstrated utility in both cellular assays and in vivo models for angiogenesis and ischemia research.
Molekulargewicht: 523.65
Reinheit: >99.99% (May vary between batches)
CAS Nummer: [2097381-85-4]
Formel: C27H33N5O4S
Target-Kategorie: HIF/HIF Prolyl-Hydroxylase,Ligands for E3 Ligase,HIF
Anwendungsbeschreibung: Solubility: DMSO:78.3 mg/mL (149.53 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.82 mM)