GNE-495 is a highly potent and selective small molecule inhibitor of MAP4K4, demonstrating an IC50 of 3.7 nM. This compound is a valuable research tool for investigating MAP4K4s role in cellular signaling, with applications in studying metabolic disorders, cancer biology, and inflammation in both in vitro and in vivo models.
Molekulargewicht:
405.42
Reinheit:
99.57% (May vary between batches)
CAS Nummer:
[1449277-10-4]
Formel:
C22H20FN5O2
Target-Kategorie:
MAPK
Anwendungsbeschreibung:
Solubility: DMSO:2 mg/mL (4.93 mM)
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten