GNE-495, CAS [[1449277-10-4]]

Product Overview

• Article Name: GNE-495, CAS [[1449277-10-4]]
• Biozol Catalog Number: BYT-ORB1296220
• Supplier Catalog Number: orb1296220
• Alternative Catalog Number: BYT-ORB1296220-1, BYT-ORB1296220-10, BYT-ORB1296220-5
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: GNE 495, GNE495, GNE-495, Inhibitor, MAP4K, MAP4K4, MAPK Kinase Kinase Kinase, inhibit

Product Description

GNE-495 is a highly potent and selective small molecule inhibitor of MAP4K4, demonstrating an IC50 of 3.7 nM. This compound is a valuable research tool for investigating MAP4K4s role in cellular signaling, with applications in studying metabolic disorders, cancer biology, and inflammation in both in vitro and in vivo models.

Product Properties

• Molecular Weight: 405.42
• Purity: 99.57% (May vary between batches)
• CAS Number: [1449277-10-4]
• Formula: C22H20FN5O2
• Target: MAPK

Application Notes

• Application Notes: Solubility: DMSO:2 mg/mL (4.93 mM)