GSK484 hydrochloride, CAS [[1652591-81-5]]

Produktübersicht

• Artikelname: GSK484 hydrochloride, CAS [[1652591-81-5]]
• Artikelnummer: BYT-ORB1296229
• Hersteller Artikelnummer: orb1296229
• Alternativnummer: BYT-ORB1296229-1, BYT-ORB1296229-1, BYT-ORB1296229-10, BYT-ORB1296229-100, BYT-ORB1296229-25, BYT-ORB1296229-5, BYT-ORB1296229-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien
• Alternative Synonym: Inhibitor, GTPL 8577, GTPL8577, GTPL-8577, GSK484, GSK-484, GSK484 hydrochloride, GSK484 Hydrochloride, GSK-484 hydrochloride, GSK-484 Hydrochloride, GSK 484, GSK 484 Hydrochloride, inhibit, PAD4, AOB 6992, AOB6992, AOB-6992, Protein Arginine Deiminase, Peptidylarginine Deiminase

Produktbeschreibung

GSK484 hydrochloride is a potent, reversible PAD4 inhibitor with IC50 values of 50 nM (without Ca) and 250 nM (with 2 mM Ca). It has been shown to enhance the radiosensitivity of colorectal cancer cells and to suppress neutrophil extracellular trap (NET) formation in both cellular and animal studies.

Produkteigenschaften

• Molekulargewicht: 510.03
• Reinheit: 99.62% (May vary between batches)
• CAS Nummer: [1652591-81-5]
• Formel: C27H32ClN5O3
• Target-Kategorie: PAD

Anwendungsbeschreibung

• Anwendungsbeschreibung: Solubility: PBS:<1 mg/mL (insoluble or slightly soluble),DMSO:247.5 mg/mL (485.27 mM),H2O:100 mg/mL (196.07 mM)