GSK484 hydrochloride, CAS [[1652591-81-5]]

Product Overview

• Article Name: GSK484 hydrochloride, CAS [[1652591-81-5]]
• Biozol Catalog Number: BYT-ORB1296229
• Supplier Catalog Number: orb1296229
• Alternative Catalog Number: BYT-ORB1296229-1, BYT-ORB1296229-1, BYT-ORB1296229-10, BYT-ORB1296229-100, BYT-ORB1296229-25, BYT-ORB1296229-5, BYT-ORB1296229-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: Inhibitor, GTPL 8577, GTPL8577, GTPL-8577, GSK484, GSK-484, GSK484 hydrochloride, GSK484 Hydrochloride, GSK-484 hydrochloride, GSK-484 Hydrochloride, GSK 484, GSK 484 Hydrochloride, inhibit, PAD4, AOB 6992, AOB6992, AOB-6992, Protein Arginine Deiminase, Peptidylarginine Deiminase

Product Description

GSK484 hydrochloride is a potent, reversible PAD4 inhibitor with IC50 values of 50 nM (without Ca) and 250 nM (with 2 mM Ca). It has been shown to enhance the radiosensitivity of colorectal cancer cells and to suppress neutrophil extracellular trap (NET) formation in both cellular and animal studies.

Product Properties

• Molecular Weight: 510.03
• Purity: 99.62% (May vary between batches)
• CAS Number: [1652591-81-5]
• Formula: C27H32ClN5O3
• Target: PAD

Application Notes

• Application Notes: Solubility: PBS:<1 mg/mL (insoluble or slightly soluble),DMSO:247.5 mg/mL (485.27 mM),H2O:100 mg/mL (196.07 mM)