Ningetinib (CT-053) is a potent, orally active small molecule inhibitor targeting Axl, VEGFR2, and c-Met kinases with low nanomolar IC50 values. It is utilized in preclinical cancer research, particularly in studies investigating tumor angiogenesis, metastasis, and resistance mechanisms in both cellular and animal models.
Molekulargewicht:
556.58
Reinheit:
99.98% (May vary between batches)
CAS Nummer:
[1394820-69-9]
Formel:
C31H29FN4O5
Target-Kategorie:
VEGFR,TAM Receptor,c-Met/HGFR
Anwendungsbeschreibung:
Solubility: DMSO:15 mg/mL (26.95 mM)
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten