Ningetinib, CAS [[1394820-69-9]]

Product Overview

• Article Name: Ningetinib, CAS [[1394820-69-9]]
• Biozol Catalog Number: BYT-ORB1296265
• Supplier Catalog Number: orb1296265
• Alternative Catalog Number: BYT-ORB1296265-1, BYT-ORB1296265-10, BYT-ORB1296265-100, BYT-ORB1296265-2, BYT-ORB1296265-25, BYT-ORB1296265-5, BYT-ORB1296265-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: inhibit, Ningetinib, HGFR, Inhibitor, Mer, AXL, Axl, cMet, cMet/HGFR, c-Met, c-Met/HGFR, CT053, CT-053, CT053PTSA, CT 053, TAM Receptor, TAMReceptor, Tyro3, VEGFR2, VEGFR, Vascular endothelial growth factor receptor

Product Description

Ningetinib (CT-053) is a potent, orally active small molecule inhibitor targeting Axl, VEGFR2, and c-Met kinases with low nanomolar IC50 values. It is utilized in preclinical cancer research, particularly in studies investigating tumor angiogenesis, metastasis, and resistance mechanisms in both cellular and animal models.

Product Properties

• Molecular Weight: 556.58
• Purity: 99.98% (May vary between batches)
• CAS Number: [1394820-69-9]
• Formula: C31H29FN4O5
• Target: VEGFR,TAM Receptor,c-Met/HGFR

Application Notes

• Application Notes: Solubility: DMSO:15 mg/mL (26.95 mM)