Compound 12d is a highly effective small molecule inhibitor of ALK5 (TGF-beta type I receptor), exhibiting potent activity with a 7 nM IC50. This inhibitor is a valuable research tool for studying TGF-beta signaling pathways in both cellular assays and animal models of fibrosis and cancer.
Molekulargewicht:
460.33
Reinheit:
99.94% (May vary between batches)
CAS Nummer:
[1352608-94-6]
Formel:
C22H18BrN7
Target-Kategorie:
ALK,TGF-beta/Smad
Anwendungsbeschreibung:
Solubility: DMSO:50 mg/mL (108.62 mM)
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten