Compound 12d is a highly effective small molecule inhibitor of ALK5 (TGF-beta type I receptor), exhibiting potent activity with a 7 nM IC50. This inhibitor is a valuable research tool for studying TGF-beta signaling pathways in both cellular assays and animal models of fibrosis and cancer.
Molecular Weight:
460.33
Purity:
99.94% (May vary between batches)
CAS Number:
[1352608-94-6]
Formula:
C22H18BrN7
Target:
ALK,TGF-beta/Smad
Application Notes:
Solubility: DMSO:50 mg/mL (108.62 mM)
* VAT and and shipping costs not included. Errors and price changes excepted