IC 86621, CAS [[404009-40-1]]

Produktübersicht

• Artikelname: IC 86621, CAS [[404009-40-1]]
• Artikelnummer: BYT-ORB1297892
• Hersteller Artikelnummer: orb1297892
• Alternativnummer: BYT-ORB1297892-1, BYT-ORB1297892-10, BYT-ORB1297892-100, BYT-ORB1297892-25, BYT-ORB1297892-5, BYT-ORB1297892-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien
• Alternative Synonym: DNA-dependent protein kinase, DNAPK, DNA-PK, DSB, Buchwald-Hartwig amination, ATP, Apoptosis, antitumor, Fries rearrangement, Inhibitor, IC 86621, IC86621, IC-86621, inhibit

Produktbeschreibung

IC 86621 is a potent, selective, and reversible ATP-competitive inhibitor of DNA-PK, exhibiting an IC50 of 120 nM. It disrupts DNA double-strand break repair with an EC50 of 68 µM in cellular assays, enhancing the antitumor effects of DNA-damaging agents in cancer research models, both in vitro and in vivo.

Produkteigenschaften

• Molekulargewicht: 221.25
• Reinheit: 99.68% (May vary between batches)
• CAS Nummer: [404009-40-1]
• Formel: C12H15NO3
• Target-Kategorie: Apoptosis,DNA-PK

Anwendungsbeschreibung

• Anwendungsbeschreibung: Solubility: DMSO:50 mg/mL (225.99 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (9.04 mM)