CU-115, CAS [[2471982-20-2]]

Produktübersicht

• Artikelname: CU-115, CAS [[2471982-20-2]]
• Artikelnummer: BYT-ORB1297961
• Hersteller Artikelnummer: orb1297961
• Alternativnummer: BYT-ORB1297961-1, BYT-ORB1297961-1, BYT-ORB1297961-10, BYT-ORB1297961-100, BYT-ORB1297961-25, BYT-ORB1297961-5, BYT-ORB1297961-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien
• Alternative Synonym: TLR8, N-(4-(3,5-bis(trifluoromethyl)phenoxy)phenyl)-2-fluoro-6-iodobenzamide, CU115, CU-115, CU 115

Produktbeschreibung

CU-115 is a potent and selective TLR8 antagonist (IC50 = 1.04 µM) that shows minimal activity against TLR7 (>50 µM). It effectively inhibits R-848-induced TNF-alpha and IL-1beta production in THP-1 cells, making it a valuable tool for studying TLR8-mediated signaling in autoimmune and inflammatory disease research.

Produkteigenschaften

• Molekulargewicht: 569.21
• Reinheit: >99.99% (May vary between batches)
• CAS Nummer: [2471982-20-2]
• Formel: C21H11F7INO2
• Target-Kategorie: TLR

Anwendungsbeschreibung

• Anwendungsbeschreibung: Solubility: DMSO:45 mg/mL (79.06 mM),10% DMSO+90% Corn Oil:2 mg/mL (3.51 mM)