CU-115, CAS [[2471982-20-2]]

Product Overview

• Article Name: CU-115, CAS [[2471982-20-2]]
• Biozol Catalog Number: BYT-ORB1297961
• Supplier Catalog Number: orb1297961
• Alternative Catalog Number: BYT-ORB1297961-1, BYT-ORB1297961-1, BYT-ORB1297961-10, BYT-ORB1297961-100, BYT-ORB1297961-25, BYT-ORB1297961-5, BYT-ORB1297961-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: TLR8, N-(4-(3,5-bis(trifluoromethyl)phenoxy)phenyl)-2-fluoro-6-iodobenzamide, CU115, CU-115, CU 115

Product Description

CU-115 is a potent and selective TLR8 antagonist (IC50 = 1.04 µM) that shows minimal activity against TLR7 (>50 µM). It effectively inhibits R-848-induced TNF-alpha and IL-1beta production in THP-1 cells, making it a valuable tool for studying TLR8-mediated signaling in autoimmune and inflammatory disease research.

Product Properties

• Molecular Weight: 569.21
• Purity: >99.99% (May vary between batches)
• CAS Number: [2471982-20-2]
• Formula: C21H11F7INO2
• Target: TLR

Application Notes

• Application Notes: Solubility: DMSO:45 mg/mL (79.06 mM),10% DMSO+90% Corn Oil:2 mg/mL (3.51 mM)