Dalpiciclib (SHR-6390) is a potent and selective oral inhibitor of CDK4/6, exhibiting antitumor activity in models such as esophageal squamous cell carcinoma. It functions by inhibiting Rb phosphorylation, inducing G1 arrest, and has demonstrated efficacy in both in vitro and in vivo studies across various cancer research fields.
Molekulargewicht:
446.54
Reinheit:
99.69% (May vary between batches)
CAS Nummer:
[1637781-04-4]
Formel:
C25H30N6O2
Target-Kategorie:
CDK
Anwendungsbeschreibung:
Solubility: DMSO:< 1 mg/mL (insoluble)
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten