Dalpiciclib (SHR-6390) is a potent and selective oral inhibitor of CDK4/6, exhibiting antitumor activity in models such as esophageal squamous cell carcinoma. It functions by inhibiting Rb phosphorylation, inducing G1 arrest, and has demonstrated efficacy in both in vitro and in vivo studies across various cancer research fields.
Molecular Weight:
446.54
Purity:
99.69% (May vary between batches)
CAS Number:
[1637781-04-4]
Formula:
C25H30N6O2
Target:
CDK
Application Notes:
Solubility: DMSO:< 1 mg/mL (insoluble)
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