Venadaparib, CAS [[1681017-83-3]]

Produktübersicht

• Artikelname: Venadaparib, CAS [[1681017-83-3]]
• Artikelnummer: BYT-ORB1298099
• Hersteller Artikelnummer: orb1298099
• Alternativnummer: BYT-ORB1298099-1, BYT-ORB1298099-1, BYT-ORB1298099-10, BYT-ORB1298099-100, BYT-ORB1298099-2, BYT-ORB1298099-25, BYT-ORB1298099-5, BYT-ORB1298099-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien
• Alternative Synonym: poly ADP ribose polymerase, solid, Venadaparib, tumors, Inhibitor, IDX 1197, IDX1197, IDX-1197, PARP, PARP2, PARP1, NOV 140101, NOV140101, NOV-140101, inhibit, anticancer

Produktbeschreibung

Venadaparib (IDX-1197) is a highly potent and selective oral PARP1/2 inhibitor, demonstrating IC50 values of 1.4 nM and 1.0 nM, respectively. It exhibits no activity against PARP-5. By blocking the repair of DNA single-strand breaks, this inhibitor is a valuable tool for investigating synthetic lethality in various solid tumor models, both in vitro and in vivo.

Produkteigenschaften

• Molekulargewicht: 406.45
• Reinheit: 99.86% (May vary between batches)
• CAS Nummer: [1681017-83-3]
• Formel: C23H23FN4O2
• Target-Kategorie: PARP

Anwendungsbeschreibung

• Anwendungsbeschreibung: Solubility: DMSO:90 mg/mL (221.43 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (12.3 mM)