Venadaparib, CAS [[1681017-83-3]]

Product Overview

• Article Name: Venadaparib, CAS [[1681017-83-3]]
• Biozol Catalog Number: BYT-ORB1298099
• Supplier Catalog Number: orb1298099
• Alternative Catalog Number: BYT-ORB1298099-1, BYT-ORB1298099-1, BYT-ORB1298099-10, BYT-ORB1298099-100, BYT-ORB1298099-2, BYT-ORB1298099-25, BYT-ORB1298099-5, BYT-ORB1298099-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: poly ADP ribose polymerase, solid, Venadaparib, tumors, Inhibitor, IDX 1197, IDX1197, IDX-1197, PARP, PARP2, PARP1, NOV 140101, NOV140101, NOV-140101, inhibit, anticancer

Product Description

Venadaparib (IDX-1197) is a highly potent and selective oral PARP1/2 inhibitor, demonstrating IC50 values of 1.4 nM and 1.0 nM, respectively. It exhibits no activity against PARP-5. By blocking the repair of DNA single-strand breaks, this inhibitor is a valuable tool for investigating synthetic lethality in various solid tumor models, both in vitro and in vivo.

Product Properties

• Molecular Weight: 406.45
• Purity: 99.86% (May vary between batches)
• CAS Number: [1681017-83-3]
• Formula: C23H23FN4O2
• Target: PARP

Application Notes

• Application Notes: Solubility: DMSO:90 mg/mL (221.43 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (12.3 mM)