Iptacopan hydrochloride, CAS [[1646321-63-2]]

Produktübersicht

• Artikelname: Iptacopan hydrochloride, CAS [[1646321-63-2]]
• Artikelnummer: BYT-ORB1298299
• Hersteller Artikelnummer: orb1298299
• Alternativnummer: BYT-ORB1298299-1, BYT-ORB1298299-1, BYT-ORB1298299-10, BYT-ORB1298299-100, BYT-ORB1298299-2, BYT-ORB1298299-200, BYT-ORB1298299-25, BYT-ORB1298299-5, BYT-ORB1298299-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien
• Alternative Synonym: factor B, Inhibitor, hemolytic, hemoglobinuria, nocturnal, paroxysmal, pathogenesis, pathway, Iptacopan hydrochloride, Iptacopan Hydrochloride, Iptacopan HCl, Iptacopan, inhibit, LNP-023, LNP023 hydrochloride, LNP023 Hydrochloride, LNP-023 Hydrochloride, LNP 023, LNP 023 Hydrochloride, LNP023, alternative, atypical, Complement System, ComplementSystem, complement, system, syndrome, PNH, uremic

Produktbeschreibung

Iptacopan hydrochloride (LNP023 hydrochloride) is a potent, selective, and orally active inhibitor of human factor B, exhibiting high-affinity reversible binding with a KD of 7.9 nM and an IC50 of 10 nM. It is a valuable research tool for studying the alternative complement pathway in both in vitro assays and in vivo disease models.

Produkteigenschaften

• Molekulargewicht: 458.98
• Reinheit: 99.89% (May vary between batches)
• CAS Nummer: [1646321-63-2]
• Formel: C25H31ClN2O4
• Target-Kategorie: Complement System

Anwendungsbeschreibung

• Anwendungsbeschreibung: Solubility: DMSO:252 mg/mL (549.04 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.89 mM),H2O:50 mg/mL (108.94 mM)