Iptacopan hydrochloride, CAS [[1646321-63-2]]

Product Overview

• Article Name: Iptacopan hydrochloride, CAS [[1646321-63-2]]
• Biozol Catalog Number: BYT-ORB1298299
• Supplier Catalog Number: orb1298299
• Alternative Catalog Number: BYT-ORB1298299-1, BYT-ORB1298299-1, BYT-ORB1298299-10, BYT-ORB1298299-100, BYT-ORB1298299-2, BYT-ORB1298299-200, BYT-ORB1298299-25, BYT-ORB1298299-5, BYT-ORB1298299-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: factor B, Inhibitor, hemolytic, hemoglobinuria, nocturnal, paroxysmal, pathogenesis, pathway, Iptacopan hydrochloride, Iptacopan Hydrochloride, Iptacopan HCl, Iptacopan, inhibit, LNP-023, LNP023 hydrochloride, LNP023 Hydrochloride, LNP-023 Hydrochloride, LNP 023, LNP 023 Hydrochloride, LNP023, alternative, atypical, Complement System, ComplementSystem, complement, system, syndrome, PNH, uremic

Product Description

Iptacopan hydrochloride (LNP023 hydrochloride) is a potent, selective, and orally active inhibitor of human factor B, exhibiting high-affinity reversible binding with a KD of 7.9 nM and an IC50 of 10 nM. It is a valuable research tool for studying the alternative complement pathway in both in vitro assays and in vivo disease models.

Product Properties

• Molecular Weight: 458.98
• Purity: 99.89% (May vary between batches)
• CAS Number: [1646321-63-2]
• Formula: C25H31ClN2O4
• Target: Complement System

Application Notes

• Application Notes: Solubility: DMSO:252 mg/mL (549.04 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.89 mM),H2O:50 mg/mL (108.94 mM)