BSJ-4-116, CAS [[2519823-34-6]]

Produktübersicht

• Artikelname: BSJ-4-116, CAS [[2519823-34-6]]
• Artikelnummer: BYT-ORB1298355
• Hersteller Artikelnummer: orb1298355
• Alternativnummer: BYT-ORB1298355-1, BYT-ORB1298355-1, BYT-ORB1298355-10, BYT-ORB1298355-100, BYT-ORB1298355-25, BYT-ORB1298355-5, BYT-ORB1298355-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien
• Alternative Synonym: Cereblon, CDK12, CDK, degrader, Cyclin dependent kinase, C1039F, cancer, BSJ4116, BSJ-4-116, BSJ 4 116, antiproliferative, Kelly, mutation, inhibit, Inhibitor, PROTACs

Produktbeschreibung

BSJ-4-116 is a potent and selective CDK12-targeting PROTAC degrader with 6 nM IC50. It disrupts DNA damage response gene transcription via premature termination and increased polyadenylation, applicable for oncology research in both cellular and animal models to study transcription-dependent vulnerabilities.

Produkteigenschaften

• Molekulargewicht: 837.38
• Reinheit: 99.09% (May vary between batches)
• CAS Nummer: [2519823-34-6]
• Formel: C40H49ClN8O8S
• Target-Kategorie: PROTACs,CDK

Anwendungsbeschreibung

• Anwendungsbeschreibung: Solubility: DMSO:250 mg/mL (298.55 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (5.97 mM)