BSJ-4-116, CAS [[2519823-34-6]]

Product Overview

• Article Name: BSJ-4-116, CAS [[2519823-34-6]]
• Biozol Catalog Number: BYT-ORB1298355
• Supplier Catalog Number: orb1298355
• Alternative Catalog Number: BYT-ORB1298355-1, BYT-ORB1298355-1, BYT-ORB1298355-10, BYT-ORB1298355-100, BYT-ORB1298355-25, BYT-ORB1298355-5, BYT-ORB1298355-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: Cereblon, CDK12, CDK, degrader, Cyclin dependent kinase, C1039F, cancer, BSJ4116, BSJ-4-116, BSJ 4 116, antiproliferative, Kelly, mutation, inhibit, Inhibitor, PROTACs

Product Description

BSJ-4-116 is a potent and selective CDK12-targeting PROTAC degrader with 6 nM IC50. It disrupts DNA damage response gene transcription via premature termination and increased polyadenylation, applicable for oncology research in both cellular and animal models to study transcription-dependent vulnerabilities.

Product Properties

• Molecular Weight: 837.38
• Purity: 99.09% (May vary between batches)
• CAS Number: [2519823-34-6]
• Formula: C40H49ClN8O8S
• Target: PROTACs,CDK

Application Notes

• Application Notes: Solubility: DMSO:250 mg/mL (298.55 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (5.97 mM)