ARC111, ARC-111, ARC 111, topoisomerase I, Topoval, Topovale
Topovale (ARC111) is a potent topoisomerase I inhibitor that suppresses hypoxia-induced HIF-1alpha accumulation. It demonstrates low nanomolar cytotoxicity against various cancer cell lines, with activity shown to be dependent on functional topoisomerase I in comparative in vitro studies using sensitive and resistant cell models.
Molekulargewicht:
421.45
Reinheit:
99.94% (May vary between batches)
CAS Nummer:
[500214-53-9]
Formel:
C23H23N3O5
Target-Kategorie:
Topoisomerase
Anwendungsbeschreibung:
Solubility: DMSO:Insoluble
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