Topovale, CAS [[500214-53-9]]

Product Overview

• Article Name: Topovale, CAS [[500214-53-9]]
• Biozol Catalog Number: BYT-ORB1298379
• Supplier Catalog Number: orb1298379
• Alternative Catalog Number: BYT-ORB1298379-1, BYT-ORB1298379-10, BYT-ORB1298379-100, BYT-ORB1298379-25, BYT-ORB1298379-5, BYT-ORB1298379-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: ARC111, ARC-111, ARC 111, topoisomerase I, Topoval, Topovale

Product Description

Topovale (ARC111) is a potent topoisomerase I inhibitor that suppresses hypoxia-induced HIF-1alpha accumulation. It demonstrates low nanomolar cytotoxicity against various cancer cell lines, with activity shown to be dependent on functional topoisomerase I in comparative in vitro studies using sensitive and resistant cell models.

Product Properties

• Molecular Weight: 421.45
• Purity: 99.94% (May vary between batches)
• CAS Number: [500214-53-9]
• Formula: C23H23N3O5
• Target: Topoisomerase

Application Notes

• Application Notes: Solubility: DMSO:Insoluble