KY19382, CAS [[2226664-93-1]]

Artikelnummer: BYT-ORB1298435
Artikelname: KY19382, CAS [[2226664-93-1]]
Artikelnummer: BYT-ORB1298435
Hersteller Artikelnummer: orb1298435
Alternativnummer: BYT-ORB1298435-1, BYT-ORB1298435-1, BYT-ORB1298435-10, BYT-ORB1298435-100, BYT-ORB1298435-25, BYT-ORB1298435-5, BYT-ORB1298435-50, BYT-ORB1298435-500
Hersteller: Biorbyt
Kategorie: Biochemikalien
Alternative Synonym: CXXC5-DVL, betacatenin, beta-catenin, bcatenin, A 3051, A3051, A-3051, 2H-Indol-2-one, 5,6-dichloro-3-[1,3-dihydro-3-(methoxyimino)-2H-indol-2-ylidene]-1,3-dihydro-Ky19382, GSK-3, GSK3, GSK-3beta, KY 19382, KY19382, KY-19382, Wnt/beta-catenin, Wnt/b-catenin, Wnt/betacatenin, Wnt, beta-catenin, betacatenin
KY19382 is a potent, orally bioavailable small molecule that dually inhibits the CXXC5-DVL interaction and GSK3beta activity (IC50s of 19 and 10 nM), thereby activating Wnt/beta-catenin signaling. It has been investigated in preclinical research for metabolic diseases, including studies using high-fat diet-induced in vivo models.
Molekulargewicht: 360.19
Reinheit: 98.06% (May vary between batches)
CAS Nummer: [2226664-93-1]
Formel: C17H11Cl2N3O2
Target-Kategorie: Wnt/beta-catenin,GSK-3
Anwendungsbeschreibung: Solubility: DMSO:5 mg/mL (13.88 mM)