KY19382 is a potent, orally bioavailable small molecule that dually inhibits the CXXC5-DVL interaction and GSK3beta activity (IC50s of 19 and 10 nM), thereby activating Wnt/beta-catenin signaling. It has been investigated in preclinical research for metabolic diseases, including studies using high-fat diet-induced in vivo models.
Molekulargewicht:
360.19
Reinheit:
98.06% (May vary between batches)
CAS Nummer:
[2226664-93-1]
Formel:
C17H11Cl2N3O2
Target-Kategorie:
Wnt/beta-catenin,GSK-3
Anwendungsbeschreibung:
Solubility: DMSO:5 mg/mL (13.88 mM)
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten