KY19382, CAS [[2226664-93-1]]

Product Overview

• Article Name: KY19382, CAS [[2226664-93-1]]
• Biozol Catalog Number: BYT-ORB1298435
• Supplier Catalog Number: orb1298435
• Alternative Catalog Number: BYT-ORB1298435-1, BYT-ORB1298435-1, BYT-ORB1298435-10, BYT-ORB1298435-100, BYT-ORB1298435-25, BYT-ORB1298435-5, BYT-ORB1298435-50, BYT-ORB1298435-500
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: CXXC5-DVL, betacatenin, beta-catenin, bcatenin, A 3051, A3051, A-3051, 2H-Indol-2-one, 5,6-dichloro-3-[1,3-dihydro-3-(methoxyimino)-2H-indol-2-ylidene]-1,3-dihydro-Ky19382, GSK-3, GSK3, GSK-3beta, KY 19382, KY19382, KY-19382, Wnt/beta-catenin, Wnt/b-catenin, Wnt/betacatenin, Wnt, beta-catenin, betacatenin

Product Description

KY19382 is a potent, orally bioavailable small molecule that dually inhibits the CXXC5-DVL interaction and GSK3beta activity (IC50s of 19 and 10 nM), thereby activating Wnt/beta-catenin signaling. It has been investigated in preclinical research for metabolic diseases, including studies using high-fat diet-induced in vivo models.

Product Properties

• Molecular Weight: 360.19
• Purity: 98.06% (May vary between batches)
• CAS Number: [2226664-93-1]
• Formula: C17H11Cl2N3O2
• Target: Wnt/beta-catenin,GSK-3

Application Notes

• Application Notes: Solubility: DMSO:5 mg/mL (13.88 mM)