API-1, CAS [[36707-00-3]]

Produktübersicht

• Artikelname: API-1, CAS [[36707-00-3]]
• Artikelnummer: BYT-ORB1298484
• Hersteller Artikelnummer: orb1298484
• Alternativnummer: BYT-ORB1298484-1, BYT-ORB1298484-1, BYT-ORB1298484-10, BYT-ORB1298484-100, BYT-ORB1298484-200, BYT-ORB1298484-25, BYT-ORB1298484-5, BYT-ORB1298484-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien
• Alternative Synonym: inhibit, NSC 177223, NSC177223, NSC-177223, Inhibitor, Akt, Akt/PKB inhibitor, Apoptosis, API 1, API1, API-1, Protein kinase B, PKB, TRAIL

Produktbeschreibung

API-1 (NSC-177223) is a selective Akt inhibitor that promotes apoptosis by triggering GSK3beta-dependent, beta-TrCP/FBXW7-mediated degradation of the anti-apoptotic protein Mcl-1. This mechanism supports its application in cancer research, particularly for studying apoptosis resistance in vitro and evaluating therapeutic potential in vivo.

Produkteigenschaften

• Molekulargewicht: 337.29
• Reinheit: 99.07% (May vary between batches)
• CAS Nummer: [36707-00-3]
• Formel: C13H15N5O6
• Target-Kategorie: Caspase,Akt,PARP,Apoptosis

Anwendungsbeschreibung

• Anwendungsbeschreibung: Solubility: DMSO:22.5 mg/mL (66.71 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.93 mM)