Sotorasib, CAS [[2296729-00-3]]

Produktübersicht

• Artikelname: Sotorasib, CAS [[2296729-00-3]]
• Artikelnummer: BYT-ORB1298716
• Hersteller Artikelnummer: orb1298716
• Alternativnummer: BYT-ORB1298716-1, BYT-ORB1298716-1, BYT-ORB1298716-1, BYT-ORB1298716-10, BYT-ORB1298716-100, BYT-ORB1298716-2, BYT-ORB1298716-25, BYT-ORB1298716-5, BYT-ORB1298716-50, BYT-ORB1298716-500
• Hersteller: Biorbyt
• Kategorie: Biochemikalien
• Alternative Synonym: Sotorasib, phosphorylation, regression, Ras, anti-tumour, AMG510, AMG-510, AMG 510, covalent, NSCLC, KRAS, KRAS G12C, inhibit, mutation, G12C, GDP-bound, Inhibitor

Produktbeschreibung

Sotorasib (AMG-510) is a selective, covalent inhibitor that targets the inactive, GDP-bound form of the KRAS G12C mutant. It potently suppresses oncogenic KRAS signaling and has demonstrated antitumor efficacy in both cellular assays and in vivo models, supporting its use in cancer research.

Produkteigenschaften

• Molekulargewicht: 560.594
• Reinheit: 99.95% (May vary between batches)
• CAS Nummer: [2296729-00-3]
• Formel: C30H30F2N6O3
• Target-Kategorie: Ras,Kras

Anwendungsbeschreibung

• Anwendungsbeschreibung: Solubility: H2O:33.33 mg/mL (59.45 mM),DMSO:247.5 mg/mL (441.5 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (8.92 mM)