Sotorasib, CAS [[2296729-00-3]]

Product Overview

• Article Name: Sotorasib, CAS [[2296729-00-3]]
• Biozol Catalog Number: BYT-ORB1298716
• Supplier Catalog Number: orb1298716
• Alternative Catalog Number: BYT-ORB1298716-1, BYT-ORB1298716-1, BYT-ORB1298716-1, BYT-ORB1298716-10, BYT-ORB1298716-100, BYT-ORB1298716-2, BYT-ORB1298716-25, BYT-ORB1298716-5, BYT-ORB1298716-50, BYT-ORB1298716-500
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: Sotorasib, phosphorylation, regression, Ras, anti-tumour, AMG510, AMG-510, AMG 510, covalent, NSCLC, KRAS, KRAS G12C, inhibit, mutation, G12C, GDP-bound, Inhibitor

Product Description

Sotorasib (AMG-510) is a selective, covalent inhibitor that targets the inactive, GDP-bound form of the KRAS G12C mutant. It potently suppresses oncogenic KRAS signaling and has demonstrated antitumor efficacy in both cellular assays and in vivo models, supporting its use in cancer research.

Product Properties

• Molecular Weight: 560.594
• Purity: 99.95% (May vary between batches)
• CAS Number: [2296729-00-3]
• Formula: C30H30F2N6O3
• Target: Ras,Kras

Application Notes

• Application Notes: Solubility: H2O:33.33 mg/mL (59.45 mM),DMSO:247.5 mg/mL (441.5 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (8.92 mM)